Recombinant Human ODC1, His-tagged

• Cat.No.: ODC1-2498H
• Product Overview: Recombinant Human ODC1 (amino acids 1-461) fused with an N terminal His tag, was expressed in E. coli.

Specification

• Cat. No.: ODC1-2498H
• Description: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
• Source: E. coli
• Molecular Mass: 53.500kDa inclusive of tags
• Protein length: 461 amino acids
• Purity: > 95 % by SDS-PAGE
• Form: Liquid
• Sequence: MGSSHHHHHHSSGLVPRGSHMGSMNNFGNEEFDCHFLDEG FTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLK ALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQL VQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEV ELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTS RLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARC VFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINP ALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVL KEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVK PLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHV GDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLM QQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASA SINV
• Storagebuffer: pH: 8.00. Constituents: 0.32% Tris HCl, 0.02% DTT, 10% Glycerol, 0.58% Sodium chloride.
• Concentration: 50 µg at 0.5 mg/ml
• Application: SDS-PAGE
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• OfficialSymbol: ODC1

Gene Information

• Gene Name: ODC1 ornithine decarboxylase 1 [ Homo sapiens ]
• Synonyms: ODC1; ornithine decarboxylase 1; ornithine decarboxylase; ODC; EC 4.1.1.17
• Gene ID: 4953
• mRNA Refseq: NM_002539
• Protein Refseq: NP_002530
• MIM: 165640
• UniProt ID: P11926
• Chromosome Location: 2p25
• Pathway: Arginine and proline metabolism; Glutathione metabolism; Metabolism; Metabolism of amino acids and derivatives
• Function: ornithine decarboxylase activity