Recombinant Human GSTM5, GST-tagged

• Cat.No.: GSTM5-13578H
• Product Overview: Recombinant Human GSTM5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-218a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GSTM5 glutathione S-transferase mu 5 [ Homo sapiens ]
• Official Symbol: GSTM5
• Synonyms: GSTM5; glutathione S-transferase mu 5; glutathione S transferase M5; glutathione S-transferase Mu 5; GST class-mu 5; glutathione S-transferase M5; glutathione S-aryltransferase M5; glutathione S-alkyltransferase M5; glutathione S-aralkyltransferase M5; S-(hydroxyalkyl)glutathione lyase M5; GTM5; GSTM5-5
• Gene ID: 2949
• mRNA Refseq: NM_000851
• Protein Refseq: NP_000842
• MIM: 138385
• UniProt ID: P46439
• Chromosome Location: 1p13.3
• Pathway: Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Glutathione conjugation, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Metabolism, organism-specific biosystem
• Function: glutathione transferase activity; transferase activity