"MYOD1" Related Products

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Recombinant Human MYOD1, GST-tagged

Cat.No.: MYOD1-166H
Product Overview: The protein was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose. Expression Vector: PGEX-4T.
Description: MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occassionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm? tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing? sarcomas and alveolar soft part sarcomas.
Source: E. coli
Species: Human
Tag: GST
AA Sequence: 0-232aa
Storage: The protein is stored in PBS bu?er at -20°C. Repeated freezethaw cycles should be avoided.
Storage Buffer: The puri?ed protein was resolved in 1M PBS(58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.0) added with 100mM GSH and 1% Triton X-100, 15% glycerol.
Gene Name: MYOD1 myogenic differentiation 1 [ Homo sapiens ]
Official Symbol: MYOD1
Synonyms: MYOD1; myogenic differentiation 1; MYF3, myogenic factor 3; myoblast determination protein 1; bHLHc1; MYOD; PUM; myf-3; myogenic factor 3; class C basic helix-loop-helix protein 1; MYF3;
Gene ID: 4654
mRNA Refseq: NM_002478
Protein Refseq: NP_002469
MIM: 159970
UniProt ID: P15172
Chromosome Location: 11p15
Pathway: C-MYB transcription factor network, organism-specific biosystem; CDO in myogenesis, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; Myogenesis, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; Regulation of nuclear SMAD2/3 signaling, organism-specific biosystem;
Function: DNA binding; E-box binding; enzyme binding; protein binding; protein heterodimerization activity; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; transcription coactivator activity; transcription factor binding; ubiquitin protein ligase binding;

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