Recombinant Human trafficking protein particle complex 2, His-tagged

• Cat.No.: TRAPPC2-356H
• Product Overview: TRAPPC2, 1-140aa, Human, His tag, E.coli

Specification

• Description: TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, this protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in TRAPPC2 are a cause of spondyloepiphyseal dysplasia tarda (SEDT). Recombinant human TRAPPC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 1mM DTT
• Molecular Mass: 18.8 kDa (163aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSGSFYF VIVGHHDNPV FEMEFLPAGK AESKDDHRHL NQFIAHAALD LVDENMWLSN NMYLKTVDKF NEWFVSAFVT AGHMRFIMLH DIRQEDGIKN FFTDVYDLYI KFSMNPFYEP NSPIRSSAFD RKVQFLGKKH LLS
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: TRAPPC2 trafficking protein particle complex 2 [ Homo sapiens ]
• Official Symbol: TRAPPC2
• Synonyms: TRAPPC2; trafficking protein particle complex 2; SEDL, spondyloepiphyseal dysplasia, late; trafficking protein particle complex subunit 2; hYP38334; MIP 2A; SEDT; TRS20; ZNF547L; sedlin; SEDL; MIP2A; TRAPPC2P1
• Gene ID: 6399
• mRNA Refseq: NM_001011658
• Protein Refseq: NP_001011658
• MIM: 300202
• UniProt ID: P0DI81
• Chromosome Location: Xp22
• Function: protein binding; transcription factor binding