Recombinant Human serpin peptidase inhibitor, clade B (ovalbumin), member 2, His-tagged

• Cat.No.: SERPINB2-624H
• Product Overview: SERPINB2, 1-415aa, Human, His tag, E.coli

Specification

• Description: SERPINB2 belongs to the serpin family. This protein inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. Recombinant human SERPINB2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 1X Phosphate Buffered Saline (pH7.4) containing 30% glycerol, 1mM DTT
• Molecular Mass: 49.0. kDa (438aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEDLCVA NTLFALNLFK HLAKASPTQN LFLSPWSISS TMAMVYMGSR GSTEDQMAKV LQFNEVGANA VTPMTPENFT SCGFMQQIQK GSYPDAILQA QAADKIHSSF RSLSSAINAS TGNYLLESVN KLFGEKSASF REEYIRLCQK YYSSEPQAVD FLECAEEARK KINSWVKTQT KGKIPNLLPE GSVDGDTRMV LVNAVYFKGK WKTPFEKKLN GLYPFRVNSA QRTPVQMMYL REKLNIGYIE DLKAQILELP YAGDVSMFLL LPDEIADVST GLELLESEIT YDKLNKWTSK DKMAEDEVEV YIPQFKLEEH YELRSILRSM GMEDAFNKGR ANFSGMSERN DLFLSEVFHQ AMVDVNEEGT EAAAGTGGVM TGRTGHGGPQ FVADHPFLFL IMHKITNCIL FFGRFSSP
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 [ Homo sapiens ]
• Official Symbol: SERPINB2
• Synonyms: SERPINB2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; PAI2, PLANH2, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; plasminogen activator inhibitor 2; HsT1201; serpin B2; monocyte Arg-serpin; urokinase inhibitor; placental plasminogen activator inhibitor; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; PAI; PAI2; PAI-2; PLANH2
• Gene ID: 5055
• mRNA Refseq: NM_001143818
• Protein Refseq: NP_001137290
• MIM: 173390
• UniProt ID: P05120
• Chromosome Location: 18q21.3
• Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Blood Clotting Cascade, organism-specific biosystem; Dissolution of Fibrin Clot, organism-specific biosystem; Hemostasis, organism-specific biosystem; Senescence and Autophagy, organism-specific biosystem
• Function: peptidase inhibitor activity; serine-type endopeptidase inhibitor activity