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Recombinant Human GART cell lysate

Cat.No.: GART-687HCL
Description: The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [ Homo sapiens ]
Official Symbol: GART
Synonyms: GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; PGFT, PRGS; trifunctional purine biosynthetic protein adenosine-3; AIRS; GARS; PAIS; PGFT; PRGS; GARTF; MGC47764;
Gene ID: 2618
mRNA Refseq: NM_000819
Protein Refseq: NP_000810
MIM: 138440
UniProt ID: P22102
Chromosome Location: 21q22.11
Pathway: 5-aminoimidazole ribonucleotide biosynthesis I, organism-specific biosystem; Inosine monophosphate biosynthesis, PRPP + glutamine =>IMP, organism-specific biosystem; Inosine monophosphate biosynthesis, PRPP + glutamine => IMP, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function: ATP binding; ligase activity; metal ion binding; methyltransferase activity; nucleotide binding; phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity; phosphoribosylglycinamide formyltransferase activity; transferase activity;

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