Recombinant Human HEXA, His-tagged
Cat.No. : | HEXA-93H |
Product Overview : | Recombinant human HEXA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | HEXA, also known as beta-hexosaminidase subunit alpha preproprotein, is an enzyme, located on the 15th chromosome. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines. Hexosaminidase A is a heterodimer composed of an alpha subunit and a beta subunit. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In phosphate buffered saline (pH7.4). |
Molecular Mass : | 59.2kDa (513aa) 50-70kDa (SDS-PAGE under reducing conditions.) |
AA Sequence : | LWPWPQNFQT SDQRYVLYPN NFQFQYDVSS AAQPGCSVLD EAFQRYRDLL FGSGSWPRPY LTGKRHTLEK NVLVVSVVTP GCNQLPTLES VENYTLTIND DQCLLLSETV WGALRGLETF SQLVWKSAEG TFFINKTEIE DFPRFPHRGL LLDTSRHYLP LSSILDTLDV MAYNKLNVFH WHLVDDPSFP YESFTFPELM RKGSYNPVTH IYTAQDVKEV IEYARLRGIR VLAEFDTPGH TLSWGPGIPG LLTPCYSGSE PSGTFGPVNP SLNNTYEFMS TFFLEVSSVF PDFYLHLGGD EVDFTCWKSN PEIQDFMRKK GFGEDFKQLE SFYIQTLLDI VSSYGKGYVV WQEVFDNKVK IQPDTIIQVW REDIPVNYMK ELELVTKAGF RALLSAPWYL NRISYGPDWK DFYIVEPLAF EGTPEQKALV IGGEACMWGE YVDNTNLVPR LWPRAGAVAE RLWSNKLTSD LTFAYERLSH FRCELLRRGV QAQPLNVGFC EQEFEQTHHH HHH |
Endotoxin : | < 1.0 eu per 1 microgram of protein (determined by lal |
Purity : | >90% by SDS - PAGE. |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Absorbance at 280nm) |
Gene Name : | HEXA hexosaminidase A (alpha polypeptide) [ Homo sapiens ] |
Official Symbol : | HEXA |
Synonyms : | HEXA; hexosaminidase A (alpha polypeptide); beta-hexosaminidase subunit alpha; GM2 gangliosidosis; Tay Sachs disease; hexosaminidase subunit A; beta-N-acetylhexosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha; TSD; MGC99608; |
Gene ID : | 3073 |
mRNA Refseq : | NM_000520 |
Protein Refseq : | NP_000511 |
MIM : | 606869 |
UniProt ID : | P06865 |
Chromosome Location : | 15q24.1 |
Pathway : | Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Glycosaminoglycan degradation, organism-specific biosystem; Glycosaminoglycan degradation, conserved biosystem; Glycosphingolipid biosynthesis - ganglio series, organism-specific biosystem; Glycosphingolipid biosynthesis - ganglio series, conserved biosystem; Glycosphingolipid biosynthesis - globo series, organism-specific biosystem; |
Function : | beta-N-acetylhexosaminidase activity; cation binding; hydrolase activity, hydrolyzing O-glycosyl compounds; protein heterodimerization activity; |
Products Types
◆ Recombinant Protein | ||
HEXA-1087H | Recombinant Human HEXA Protein, MYC/DDK-tagged | +Inquiry |
HEXA-2488R | Recombinant Rat HEXA Protein, His (Fc)-Avi-tagged | +Inquiry |
HEXA-1890R | Recombinant Rhesus Macaque HEXA Protein, His (Fc)-Avi-tagged | +Inquiry |
Hexa-1116M | Recombinant Mouse Hexa Protein, MYC/DDK-tagged | +Inquiry |
HEXA-4138M | Recombinant Mouse HEXA Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HEXA-548HCL | Recombinant Human HEXA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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