Active Recombinant Human PPIB Protein

• Cat.No.: PPIB-63H
• Product Overview: Recombinant Human PPIB Protein without tag was expressed in E.coli.

Specification

• Description: The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
• Source: E. coli
• Species: Human
• Bio-activity: Specific activity is > 1,500 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.
• Molecular Mass: 21.2 kDa
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method
• Purity: >95% by SDS-PAGE
• Storage: Store at -20 to -80 centigrade in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage Buffer: In 20mM Tris 8.0, 20mM NaCl, 0.5mM DTT, 10% glycerol.

Gene Information

• Gene Name: PPIB peptidylprolyl isomerase B [ Homo sapiens (human) ]
• Official Symbol: PPIB
• Synonyms: PPIB; peptidylprolyl isomerase B; B; OI9; CYPB; SCYLP; CYP-S1; HEL-S-39; peptidyl-prolyl cis-trans isomerase B; PPIase B; S-cyclophilin; cyclophilin-like protein; epididymis secretory protein Li 39; peptidylprolyl isomerase B (cyclophilin B); rotamase B; EC 5.2.1.8
• Gene ID: 5479
• mRNA Refseq: NM_000942
• Protein Refseq: NP_000933
• MIM: 123841
• UniProt ID: P23284