Recombinant Human MPG, His-tagged

• Cat.No.: MPG-29356TH
• Product Overview: Recombinant full length Human MPG (amino acids 1-298) with an C terminal His tag; 306 amino acids including tag, MWt 33.9kDa.

Specification

• Description: DNA-3-methyladenine glycosylase is an enzyme that in humans is encoded by the MPG gene.
• Protein length: 298 amino acids
• Conjugation: HIS
• Molecular Weight: 33.900kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:30% Glycerol, 0.32% Tris HCl, 1% DTT, 1.17% Sodium chloride, 0.03% EDTA
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MVTPALQMKKPKQFCRRMGQKKQRP ARAGQPHSSSDAAQAPAEQPHSSSD AAQAPCPRERCLGPPTTPGPYRSIY FSSPKGHLTRLGLEFFDQPAVPLAR AFLGQVLVRRLPNGTELRGRIVETE AYLGPEDEAAHSRGGRQTPRNRGMF MKPGTLYVYIIYGMYFCMNISSQGD GACVLLRALEPLEGLETMRQLRSTL RKGTASRVLKDRELCSGPSKLCQAL AINKSFDQRDLAQDEAVWLERGPLE PSEPAVVAAARVGVGHAGEWARKPL RFYVRGSPWVSVVDRVAEQDTQALE HHHHHH
• Sequence Similarities: Belongs to the DNA glycosylase MPG family.

Gene Information

• Gene Name: MPG N-methylpurine-DNA glycosylase [ Homo sapiens ]
• Official Symbol: MPG
• Synonyms: MPG; N-methylpurine-DNA glycosylase; DNA-3-methyladenine glycosylase; alkyladenine DNA glycosylase; MDG
• Gene ID: 4350
• mRNA Refseq: NM_001015052
• Protein Refseq: NP_001015052
• MIM: 156565
• Uniprot ID: P29372
• Chromosome Location: 16p13.3
• Pathway: Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem
• Function: DNA binding; alkylbase DNA N-glycosylase activity; catalytic activity; damaged DNA binding; hydrolase activity