Recombinant Human TAGLN, His-tagged

• Cat.No.: TAGLN-30926TH
• Product Overview: Recombinant fragment, corresponding to amino acids 4-201 of Human SM22 alpha with N terminal His tag; 198 amino acids, 26kDa.

Specification

• Description: The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 115 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Store at 4°C. Upon reconstitution store at -80oC.
• Sequences of amino acids: KGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVG RPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPE NPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGK DMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEH KREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPR QIIS
• Sequence Similarities: Belongs to the calponin family.Contains 1 calponin-like repeat.Contains 1 CH (calponin-homology) domain.

Gene Information

• Gene Name: TAGLN transgelin [ Homo sapiens ]
• Official Symbol: TAGLN
• Synonyms: TAGLN; transgelin; DKFZp686P11128; SM22; SM22 alpha; SMCC; TAGLN1; transgelin variant 2; WS3 10
• Gene ID: 6876
• mRNA Refseq: NM_001001522
• Protein Refseq: NP_001001522
• MIM: 600818
• Uniprot ID: Q01995
• Chromosome Location: 11q23.2
• Function: actin binding