Cat.No. :	TAGLN-30926TH
Product Overview :	Recombinant fragment, corresponding to amino acids 4-201 of Human SM22 alpha with N terminal His tag; 198 amino acids, 26kDa.
Description :	The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
Conjugation :	HIS
Source :	E. coli
Form :	Lyophilised:Reconstitute with 115 μl aqua dest.
Storage buffer :	Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage :	Store at 4°C. Upon reconstitution store at -80oC.
Sequences of amino acids :	KGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVG RPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPE NPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGK DMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEH KREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPR QIIS
Sequence Similarities :	Belongs to the calponin family.Contains 1 calponin-like repeat.Contains 1 CH (calponin-homology) domain.

Gene Name :	TAGLN transgelin [ Homo sapiens ]
Official Symbol :	TAGLN
Synonyms :	TAGLN; transgelin; DKFZp686P11128; SM22; SM22 alpha; SMCC; TAGLN1; transgelin variant 2; WS3 10;
Gene ID :	6876
mRNA Refseq :	NM_001001522
Protein Refseq :	NP_001001522
MIM :	600818
Uniprot ID :	Q01995
Chromosome Location :	11q23.2
Function :	actin binding;

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