||Recombinant human RQCD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
||RQCD1, also known as RCD1, is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation. It down-regulates MYB- and JUN-dependent transcription and may play a role in cell differentiation. RQCD1 also plays a role in retinoic acid-controlled lung development.
||MGSSHHHHHH SSGLVPRGSH MHSLATAAPV PTTLAQVDRE KIYQWINELS SPETRENALL ELSKKRESVP DLAPMLWHSF GTIAALLQEI VNIYPSINPP TLTAHQSNRV CNALALLQCV ASHPETRSAF LAAHIPLFLY PFLHTVSKTR PFEYLRLTSL GVIGALVKTD EQEVINFLLT TEIIPLCLRI MESGSELSKT VATFILQKIL LDDTGLAYIC QTYERFSHVA MILGKMVLQL SKEPSARLLK HVVRCYLRLS DNPRAREALR QCLPDQLKDT TFAQVLKDDT TTKRWLAQLV KNLQEGQVTD PRGIPLPPQ.
||> 95% by SDS – PAGE.
||35.7 kDa (319aa) confirmed by MALDI-TOF.
||Liquid. 20mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT.
||1mg/ml (determined by Bradford assay).
||Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.