Active Recombinant Human AMBRA1 Protein, Myc/DDK-tagged

• Cat.No.: AMBRA1-01H
• Product Overview: Purified recombinant protein of Homo sapiens autophagy/beclin-1 regulator 1 (AMBRA1) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Bio-activity: Binding assay
• Molecular Mass: 132.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: AMBRA1 autophagy and beclin 1 regulator 1 [ Homo sapiens (human) ]
• Official Symbol: AMBRA1
• Synonyms: AMBRA1; autophagy and beclin 1 regulator 1; DCAF3; WDR94; activating molecule in BECN1-regulated autophagy protein 1; DDB1 and CUL4 associated factor 3; WD repeat domain 94; activating molecule in beclin-1-regulated autophagy; autophagy/beclin-1 regulator 1
• Gene ID: 55626
• mRNA Refseq: NM_017749
• Protein Refseq: NP_060219
• MIM: 611359
• UniProt ID: Q9C0C7