| Description : |
Gamma-aminobutyric acid receptor subunit alpha-1, GABA(A) receptor subunit alpha-1; Gamma-aminobutyric acid receptor subunit beta-3, GABA(A) receptor subunit beta-3; Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2 Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel. The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity. |
| Source : |
Mammalian cell |
| Species : |
Human |
| Tag : |
Strep |
| Form : |
Liquid |
| Endotoxin : |
< 0.01 EU/μg of the protein |
| Purity : |
75% |
| Stability : |
Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade |
| Storage : |
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : |
20 mM HEPES (pH 7.5), 150 mM NaCl, 0.005% GDN, 0.0005% CHS |
| Shipping : |
It is shipped out with blue ice. |
