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Recombinant Human KTELC1 Protein, MYC/DDK-tagged

Cat.No. : KTELC1-1014H
Product Overview : Recombinant human KTELC1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 46 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : protein O-glucosyltransferase 1 [ Homo sapiens ]
Official Symbol : KTELC1
Synonyms : CLP46, MDSRP, C3orf9, MDS010, hCLP46, KDELCL1, MGC32995
Gene ID : 56983
Protein Refseq : NP_689518
MIM : 615618

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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