"LYPD8" Related Products

Recombinant Human LYPD8 protein, Fc-tagged

Cat.No.: LYPD8-334H
Product Overview: Recombinant Human LYPD8(Leu20-Asn215) fused with Fc of Human IgG1 at C-terminal was expressed in CHO.
Description: Ly6/PLAUR domain containing 8 (LYPD8), is a GPI-linked protein with structural similarity to the urokinase-type plasminogen activator receptor (uPAR). Mature human LYPD8 contains one uPAR/Ly6 domain and a Ser/Thr/Pro-rich (STP) region that may serve as a target for protease mediated shedding as has been shown for the related C4.4A/LYPD3 molecule. Mature human LYPD8 shares 40% amino acid sequence identity with mouse and rat LYPD8.
Source: CHO
Species: Human
Tag: Fc
Predicted N Terminal: Leu20
Form: Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human LYPD8 Fc Chimera is coated at 2 µg/mL, Recombinant Human Galectin‑3 binds with a typical ED50 = 90-540 ng/mL.
Molecular Mass: Predicted Molecular Mass: 48 kDa;SDS-PAGE: 85-100 kDa, reducing conditions.
Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 500 μg/mL in PBS.
Gene Name: LYPD8 LY6/PLAUR domain containing 8 [ Homo sapiens ]
Official Symbol: LYPD8
Synonyms: phospholipase inhibitor
Gene ID: 646627
mRNA Refseq: NM_001085474
Protein Refseq: NP_001078943
MIM: 617067
UniProt ID: Q6UX82
Chromosome Location: 1q44
Products Types ◆ Recombinant Protein

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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