Recombinant Human PA28A Protein, His-tagged
| Cat.No. : | PA28A-305H |
| Product Overview : | Recombinant Human PA28A Protein is produced by Bacteria expression system. This protein is fused with a His tag. |
- Specification
- Gene Information
- Related Products
| Description : | PA28 (also called the 11S regulatory complex) is another activator of the 20S proteasome, which assembles on either one or both ends of the 20S proteasome in an ATP-independent manner. PA28 can greatly enhance the peptidase activities of the 20S proteasome, but not for degradation of ubiquitinated proteins. The PA28 activator is a complex of two alternating homologous subunits, PA28α and PA28β, which assembles as a hexameric ring with an α3β3 stoichiometry. PA28α and PA28β are induced by interferon. Functionally, PA28 enhances the generation of class I peptides for antigen presentation. The third subunit, PA28γ, was recently identified in the nucleus. Recombinant PA28α and PA28β form a heptomeric ring; whereas PA28γ forms a hexameric ring. All of them can stimulate the peptidase activities of the 20S proteasome. |
| Source : | Bacteria |
| Species : | Human |
| Tag : | His |
| Form : | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| Molecular Mass : | 28.7 kDa |
| Purity : | > 95 % by SDS-PAGE |
| Storage : | Store at -80 centigrade; avoid multiple freeze-thaw cycles. |
| Gene Name : | PSME1 proteasome activator subunit 1 ( Homo sapiens (human) ) |
| Official Symbol : | PSME1 |
| Synonyms : | PSME1; IFI5111; REGalpha; PA28alpha; PA28-alpha; PA28 alpha |
| Gene ID : | 5720 |
| mRNA Refseq : | NM_006263 |
| Protein Refseq : | NP_006254 |
| UniProt ID : | Q06323 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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