Recombinant Human PLS3 Protein, MYC/DDK-tagged

• Cat.No.: PLS3-2156H
• Product Overview: Recombinant human PLS3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 68 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PLS3 plastin 3 [ Homo sapiens ]
• Official Symbol: PLS3
• Synonyms: BMND18; T-plastin
• Gene ID: 5358
• mRNA Refseq: NM_001136025
• Protein Refseq: NP_001129497
• MIM: 300131
• UniProt ID: P13797