Recombinant Human PTGDS Protein, MYC/DDK-tagged

• Cat.No.: PTGDS-3110H
• Product Overview: Recombinant Human PTGDS protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 20.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PTGDS prostaglandin D2 synthase 21kDa (brain) [ Homo sapiens ]
• Official Symbol: PTGDS
• Synonyms: L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
• Gene ID: 5730
• mRNA Refseq: NM_000954
• Protein Refseq: NP_000945
• MIM: 176803
• UniProt ID: P41222