Recombinant Human PTGES Protein (M1-L152 end), His tagged

• Cat.No.: PTGES-1247H
• Product Overview: Recombinant Human PTGES(M1-L152 end)-3C-eGFP-10His Protein was expressed in Insect cell.

Specification

• Description: Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively.
• Source: Insect cell
• Species: Human
• Tag: His
• Form: Liquid
• Protein Length: M1-L152 end
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Formulation:
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: PTGES prostaglandin E synthase [ Homo sapiens (human) ]
• Official Symbol: PTGES
• Synonyms: PTGES; prostaglandin E synthase; MGST1L1; glutathione S transferase 1 like 1; MGST IV; MGST1 L1; MGST1 like 1; microsomal glutathione S transferase 1 like 1; microsomal prostaglandin E synthase 1; p53 induced gene 12; PIG12; TP53I12; tumor protein p53 inducible protein 12; MGST1-like 1; p53-induced gene 12 protein; p53-induced apoptosis protein 12; glutathione S-transferase 1-like 1; microsomal prostaglandin E synthase-1; microsomal glutathione S-transferase 1-like 1; PGES; MPGES; PP102; PP1294; MGST-IV; mPGES-1; MGST1-L1; MGC10317
• Gene ID: 9536
• mRNA Refseq: NM_004878
• Protein Refseq: NP_004869
• MIM: 605172
• UniProt ID: O14684