| Description : |
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. |
| Source : |
E. coli |
| Species : |
Human |
| Form : |
lyophilized |
| Molecular Mass : |
4.118 kDa |
| Protein Length : |
593 |
| AA Sequence : |
MGTARIAPGLALLLCCPVLSSAYAL VDADDVMTKEEQIFLLHRAQAQCEK RLKEVLQRPASIMESDKGWTSASTS GKPRKDKASGKLYPESEEDKEAPTG SRYRGRPCLPEWDHILCWPLGAPGE VVAVPCPDYIYDFNHKGHAYRRCDR NGSWELVPGHNRTWANYSECVKFLT NETREREVFDRLGMIYTVGYSVSLA SLTVAVLILAYFRRLHCTRNYIHMH LFLSFMLRAVSIFVKDAVLYSGATL DEAERLTEEELRAIAQAPPPPATAA AGYAGCRVAVTFFLYFLATNYYWIL VEGLYLHSLIFMAFFSEKKYLWGFT VFGWGLPAVFVAVWVSVRATLANTG CWDLSSGNKKWIIQVPILASIVLNF ILFINIVRVLATKLRETNAGRCDTR QQYRKLLKSTLVLMPLFGVHYIVFM ATPYTEVSGTLWQVQMHYEMLFNSF QGFFVAIIYCFCNGEVQAEIKKSWS RWTLALDFKRKARSGSSSYSYGPMV SHTSVTNVGPRVGLGLPLSPRLLPT ATTNGHPQLPGHAKPGTPALETLET TPPAMAAPKDDGFLNGSCSGLDEEA SGPERPPALLQEEWETVM |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
4°C |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution (reconst). |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
