Recombinant Human RBX1

• Cat.No.: RBX1-31333TH
• Product Overview: Recombinant full lengthhuman ROC1 protein, 12 kDa.

Specification

• Description: This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.
• Source: E. coli
• Tissue specificity: Widely expressed.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the RING-box family.Contains 1 RING-type zinc finger.

Gene Information

• Gene Name: RBX1 ring-box 1, E3 ubiquitin protein ligase [ Homo sapiens ]
• Official Symbol: RBX1
• Synonyms: RBX1; ring-box 1, E3 ubiquitin protein ligase; ring box 1; E3 ubiquitin-protein ligase RBX1; BA554C12.1; regulator of cullins 1; RNF75; ROC1
• Gene ID: 9978
• mRNA Refseq: NM_014248
• Protein Refseq: NP_055063
• MIM: 603814
• Uniprot ID: P62877
• Chromosome Location: 22q13.2
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem
• Function: NEDD8 ligase activity; ligase activity; metal ion binding; protein binding; contributes_to ubiquitin-protein ligase activity