Recombinant Human RELB Protein, Myc/DDK-tagged

• Cat.No.: RELB-5321H
• Product Overview: Recombinant protein of human v-rel reticuloendotheliosis viral oncogene homolog B (RELB) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin; nucleus; and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 62 kDa
• AA Sequence: MLRSGPASGPSVPTGRAMPSRRVAR PPAAPELGALGSPDLSSLSLAVSRS TDELEIIDEYIKENGFGLDGGQPGP GEGLPRLVSRGAASLSTVTLGPVAP PATPPPWGCPLGRLVSPAPGPGPQP HLVITEQPKQRGMRFRYECEGRSAG SILGESSTEASKTLPAIELRDCGGL REVEVTACLVWKDWPHRVHPHSLVG KDCTDGICRVRLRPHVSPRHSFNNL GIQCVRKKEIEAAIERKIQLGIDPY NAGSLKNHQEVDMNVVRICFQASYR DQQGQMRRMDPVLSEPVYDKKSTNT SELRICRINKESGPCTGGEELYLLC DKVQKEDISVVFSRASWEGRADFSQ ADVHRQIAIVFKTPPYEDLEIVEPV TVNVFLQRLTDGVCSEPLPFTYLPR DHDSYGVDKKRKRGMPDVLGELNSS DPHGIESKRRKKKPAILDHFLPNHG SGPFLPPSALLPDPDFFSGTVSLPG LEPPGGPDLLDDGFAYDPTAPTLFT MLDLLPPAPPHASAVVCSGGAGAVV GETPGPEPLTLDSYQAPGPGDGGTA SLVGSNMFPNHYREAAFGGGLLSPG PEAT
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: RELB RELB proto-oncogene, NF-kB subunit [ Homo sapiens (human) ]
• Official Symbol: RELB RELB proto-oncogene, NF-kB subunit [ Homo sapiens (human) ]
• Synonyms: RELB; RELB proto-oncogene, NF-kB subunit; IREL; I-REL; IMD53; REL-B; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
• Gene ID: 5971
• mRNA Refseq: NM_006509
• Protein Refseq: NP_006500
• MIM: 604758
• UniProt ID: Q01201