Recombinant Human SERPINH1 Protein, His-tagged

• Cat.No.: SERPINH1-576H
• Product Overview: Recombinant human SERPINH1 protein with His tag was expressed in HEK293.

Specification

• Description: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: 45.3 kDa
• Protein Length: 418
• AA Sequence: MRSLLLLSAFCLLEAALAAEVKKPA AAAAPGTAEKLSPKAATLAERSAGL AFSLYQAMAKDQAVENILVSPVVVA SSLGLVSLGGKATTASQAKAVLSAE QLRDEEVHAGLGELLRSLSNSTARN VTWKLGSRLYGPSSVSFADDFVRSS KQHYNCEHSKINFRDKRSALQSINE WAAQTTDGKLPEVTKDVERTDGALL VNAMFFKPHWDEKFHHKMVDNRGFM VTRSYTVGVMMMHRTGLYNYYDDEK EKLQIVEMPLAHKLSSLIILMPHHV EPLERLEKLLTKEQLKIWMGKMQKK AVAISLPKGVVEVTHDLQKHLAGLG LTEAIDKNKADLSRMSGKKDLYLAS VFHATAFELDTDGNPFDQDIYGREE LRSPKLFYADHPFIFLVRDTQSGSL LFIGRLVRPKGDKMRDEL
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) [ Homo sapiens (human) ]
• Official Symbol: SERPINH1
• Synonyms: SERPINH1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); CBP1, CBP2, serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) , serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2 , SERPINH2; serpin H1; colligen; HSP47; colligin-1; colligin-2; 47 kDa heat shock protein; arsenic-transactivated protein 3; rheumatoid arthritis antigen A-47; cell proliferation-inducing gene 14 protein; rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2); CBP1; CBP2; OI10; gp46; AsTP3; PIG14; PPROM; RA-A47; SERPINH2
• Gene ID: 871
• mRNA Refseq: NM_001207014
• Protein Refseq: NP_001193943
• MIM: 600943
• UniProt ID: P50454