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Recombinant Mouse Crppa Protein, Myc/DDK-tagged

Cat.No. : Crppa-1425M
Product Overview : Purified recombinant protein of mouse full-length RIKEN cDNA 4930579E17 gene (cDNA clone MGC:106594 IMAGE:30610161), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
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Description : Cytidylyltransferase required for protein O-linked mannosylation. Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not Involved in dolichol production.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 31 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Crppa CDP-L-ribitol pyrophosphorylase A [ Mus musculus (house mouse) ]
Official Symbol : Crppa
Synonyms : Crppa; CDP-L-ribitol pyrophosphorylase A; I; Ispd; AV040780; 4930579E17Rik; D-ribitol-5-phosphate cytidylyltransferase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein; isoprenoid synthase domain containing; isoprenoid synthase domain-containing protein; notch1-induced protein; EC 2.7.7.40
Gene ID : 75847
mRNA Refseq : NM_178629
Protein Refseq : NP_848744
UniProt ID : Q5RJG7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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