Recombinant Mouse Dcun1d5 Protein, Myc/DDK-tagged

• Cat.No.: Dcun1d5-2486M
• Product Overview: Purified recombinant protein of mouse full-length DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) (Dcun1d5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Contributes to the neddylation of all cullins by transfering NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate to cell proliferation and anchorage-independent cell growth.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 27.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dcun1d5 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) [ Mus musculus (house mouse) ]
• Official Symbol: Dcun1d5
• Synonyms: Dcun1d5; DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae); DCNL5; AW060460; 3110001A18Rik; 4833420K19Rik; D430047L21Rik; DCN1-like protein 5; DCUN1 domain-containing protein 5; defective in cullin neddylation protein 1-like protein 5; squamous cell carcinoma-related oncogene 5
• Gene ID: 76863
• mRNA Refseq: NM_029775
• Protein Refseq: NP_084051
• UniProt ID: Q9CXV9