Recombinant Mouse Klhl42 Protein, Myc/DDK-tagged

• Cat.No.: Klhl42-3721M
• Product Overview: Purified recombinant protein of mouse full-length kelch-like 42 (Klhl42), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 55.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Klhl42 kelch-like 42 [ Mus musculus (house mouse) ]
• Official Symbol: Klhl42
• Synonyms: Klhl42; kelch-like 42; Ctb9; Klhdc; Klhdc5; AI450355; mKIAA1340; A330079N23Rik; C230080I20Rik; kelch-like protein 42; cullin-3-binding protein 9; kelch domain containing 5; kelch domain-containing protein 5
• Gene ID: 232539
• mRNA Refseq: NM_001081237
• Protein Refseq: NP_001074706
• UniProt ID: Q8BFQ9