Recombinant Mouse Zyg11b Protein, Myc/DDK-tagged
Cat.No. : | Zyg11b-7134M |
Product Overview : | Purified recombinant protein of Mouse zyg-ll family member B, cell cycle regulator (Zyg11b), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZER1 to target substrates bearing N-terminal glycine degrons for proteasomal degradation. Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 84 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Zyg11b zyg-ll family member B, cell cycle regulator [ Mus musculus (house mouse) ] |
Official Symbol : | Zyg11b |
Synonyms : | Zyg11b; zyg-ll family member B, cell cycle regulator; Gm431; D4Mgi2; D4Mgi23; mKIAA1730; 1110046I03Rik; 2810482G21Rik; protein zyg-11 homolog B; zyg-ll homolog B |
Gene ID : | 414872 |
mRNA Refseq : | NM_001033634 |
Protein Refseq : | NP_001028806 |
UniProt ID : | Q3UFS0 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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