Heavy-labeled Full-length Proteins

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Heavy-labeled Full-length Proteins

Due to the costly manners of producing isotopic chemicals and heterologous proteins, an economic 15N/13C isotopic labeling strategy is critically in demand. Stable isotope labeling by amino acids in cell culture (SILAC) is a multiplexing quantitative proteomic method that incorporates isotopically (heavy) labeled amino acids metabolically into the whole proteome.

Creative BioMart now offers an extensive collection of Mass Spectrometry (MS) standards for 6,000 proteins. Produced in HEK293T cells and labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, these full-length proteins with appropriate post-translational modifications are ideal identification and quantification standards.

Advantages

• Authentic post-translational modifications
• High data consistency
• High reproducibility
• Identifying the best SRM and MRM transitions
• Suitable for most types of MS equipment
• Over 90% incorporation efficiency