Recombinant Human ANKRD10 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ANKRD10-738H |
Product Overview : | ANKRD10 MS Standard C13 and N15-labeled recombinant protein (NP_060134) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | ANKRD10 (Ankyrin Repeat Domain 10) is a Protein Coding gene. An important paralog of this gene is ANKRD6. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Molecular Mass : | 44.6 kDa |
AA Sequence : | MSAAGAGAGVEAGFSSEELLSLRFP LHRACRDGDLATLCSLLQQTPHAHL ASEDSFYGWTPVHWAAHFGKLECLV QLVRAGATLNVSTTRYAQTPAHIAA FGGHPQCLVWLIQAGANINKPDCEG ETPIHKAARSGSLECISALVANGAH VDLRNASGLTAADIAQTQGFQECAQ FLLNLQNCHLNHFYNNGILNGGHQN VFPNHISVGTNRKRCLEDSEDFGVK KARTEAQSLDSAVPLTNGDTEDDAD KMHVDREFAVVTDMKNSSSVSNTLT NGCVINGHLDFPSTTPLSGMESRNG QCLTGTNGISSGLAPGQPFPSSQGS LCISGTEEPEKTLRANPELCGSLHL NGSPSSCIASRPSWVEDIGDNLYYG HYHGFGDTAESIPELNSVVEHSKSV KVQERYDSAVLGTMHLHHGSTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ANKRD10 ankyrin repeat domain 10 [ Homo sapiens (human) ] |
Official Symbol : | ANKRD10 |
Synonyms : | Ankrd10; Ankyrin repeat domain-containing protein 10; ANR10_HUMAN; RP11-120J20.3; ANKRD10 |
Gene ID : | 55608 |
mRNA Refseq : | NM_017664 |
Protein Refseq : | NP_060134 |
UniProt ID : | Q9NXR5 |
Products Types
◆ Recombinant Protein | ||
ANKRD10-157R | Recombinant Rhesus Macaque ANKRD10 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ankrd10-208M | Recombinant Mouse Ankrd10 Protein, MYC/DDK-tagged | +Inquiry |
ANKRD10-571H | Recombinant Human ANKRD10 protein, GST-tagged | +Inquiry |
ANKRD10-9664H | Recombinant Human ANKRD10, His-tagged | +Inquiry |
ANKRD10-329R | Recombinant Rhesus monkey ANKRD10 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ANKRD10-8857HCL | Recombinant Human ANKRD10 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (5)
Write a reviewIn addition to its high-quality attributes, the manufacturer of the ANKRD10 protein offers exemplary technical support.
the ANKRD10 protein exhibits superior performance across a range of experimental applications.
The ANKRD10 protein is renowned for its exceptional quality, making it a perfect match for my experimental requirements.
Its versatility allows for its successful implementation in diverse areas such as molecular biology, cellular assays, and protein-protein interactions.
This adaptability ensures that the ANKRD10 protein can effectively address my specific research objectives, enabling breakthrough discoveries.
Q&As (28)
Ask a questionThe precise biochemical functions of ANKRD10 are still under investigation. It has been proposed that ANKRD10 may act as a scaffold protein, regulating protein-protein interactions and potentially influencing downstream signaling events. However, further research is needed to elucidate its exact biochemical functions.
The expression of ANKRD10 in different tissues is still being investigated. However, studies have shown that ANKRD10 is widely expressed in various tissues, including the brain, heart, skeletal muscle, liver, and kidney. Its expression levels may vary depending on the specific tissue and developmental stage.
The specific cellular processes and signaling pathways involving ANKRD10 are still being investigated. Some studies indicate its potential involvement in EMT, gene regulation, and cellular migration. However, more research is needed to comprehensively define its roles in cellular processes and pathways.
Post-translational modifications of ANKRD10 have not been extensively studied. However, phosphorylation sites have been identified on ANKRD10, suggesting that it may be subject to regulatory modifications similar to other proteins.
Yes, ANKRD10 mutations can be inherited. Mutations in the ANKRD10 gene can be passed down through generations, causing genetic disorders or diseases in affected individuals.
As of my knowledge, there are limited animal models or knockout studies specifically focusing on ANKRD10. Further investigations using animal models may help in understanding its function and potential implications in health and disease.
Although not well characterized, studies have suggested potential associations between ANKRD10 and diseases such as cancer, cardiovascular diseases, and neurological disorders. However, more research is needed to establish the exact mechanisms and significance of these associations.
ANKRD10 has been reported to interact with various proteins, including TNF receptor-associated factor 6 (TRAF6), β-catenin, and the retinoblastoma protein (RB). These interactions suggest potential roles for ANKRD10 in cellular signaling and gene regulation.
ANKRD10 appears to be predominantly localized in the nucleus of cells, suggesting its involvement in nuclear processes such as gene regulation. However, further studies are needed to fully understand its subcellular localization and dynamics.
Targeting ANKRD10 for therapeutic interventions would require a comprehensive understanding of its functions and involvement in specific diseases or pathways. Further research is needed to determine if ANKRD10 could be a viable therapeutic target and develop strategies to modulate its activity.
Currently, there are no known small molecule inhibitors or activators specifically targeting ANKRD10. Developing such compounds would require a detailed understanding of ANKRD10's structure, function, and involvement in specific pathways or disease mechanisms.
Currently, there is limited information regarding ANKRD10 mutations and their potential association with genetic disorders. Further research is necessary to fully understand the impact of ANKRD10 mutations on health.
The involvement of ANKRD10 in specific signaling pathways is not well-documented. However, its ankyrin repeat domains suggest potential interactions with other proteins involved in cellular signaling pathways.
Yes, alternative splicing isoforms of ANKRD10 have been reported in different studies. These isoforms may have distinct functions and tissue-specific expression patterns. Further research is needed to fully characterize the alternative splicing isoforms of ANKRD10 and their functional significance.
Genetic variants and polymorphisms in the ANKRD10 gene have been identified in different populations through genome-wide association studies (GWAS) and genetic sequencing. These variants could potentially be associated with various traits or diseases, but their specific functional consequences are yet to be determined.
ANKRD10 is found in multiple vertebrate species, including mammals, birds, and fish. This suggests that it is evolutionarily conserved and may have important functions across different organisms.
Yes, ANKRD10 contains several ankyrin repeat domains. Ankyrin repeats are structural motifs commonly found in proteins involved in protein-protein interactions and often mediate binding to other proteins or domains.
ANKRD10 has been found to interact with various proteins, including TRAF6, β-catenin, and RB, suggesting potential functional partners or regulators. However, more research is needed to fully elucidate the regulatory mechanisms and functional relationships involving ANKRD10.
As of now, there are no known animal models specifically targeting ANKRD10. Generating animal models, such as knockout mice, to study ANKRD10's functions and physiological relevance would provide valuable insights into its roles in different biological processes.
Several databases such as UniProt, NCBI, and Ensembl provide information on the ANKRD10 protein and its associated gene. Researchers can also utilize various protein interaction databases and analysis tools to investigate ANKRD10's potential interactions and functions.
Currently, there are no known drugs or therapies that specifically target ANKRD10. As research progresses, a better understanding of ANKRD10's role in diseases may contribute to the development of targeted therapies in the future.
ANKRD10 mutations have been associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and intellectual disability (ID). However, the precise role of ANKRD10 in these developmental disorders is still being elucidated, and more research is needed to fully understand its contribution.
Currently, there is limited information regarding specific diseases or disorders caused by mutations in the ANKRD10 gene. However, ANKRD10 has been implicated in neurodevelopmental disorders, including autism spectrum disorder (ASD) and intellectual disability (ID). Further research is required to understand the full impact of ANKRD10 mutations on human health.
At present, there are no validated diagnostic tests utilizing ANKRD10 as a specific marker for any diseases. More research is necessary to explore the diagnostic potential of ANKRD10 in various conditions.
It is currently unclear if ANKRD10 can be used as a biomarker for any specific diseases. Further studies are needed to investigate its potential as a diagnostic or prognostic biomarker in various diseases or conditions.
There is limited research regarding the role of ANKRD10 in cancer. However, some studies suggest that ANKRD10 may play a role in tumorigenesis and cancer progression. For example, ANKRD10 has been implicated in promoting cell migration and invasion in hepatocellular carcinoma. Further studies are needed to fully understand the involvement of ANKRD10 in cancer and its potential as a therapeutic target.
There is limited information on the involvement of ANKRD10 in development. However, it has been suggested that ANKRD10 may contribute to neurodevelopmental disorders, highlighting a potential role in the development and function of the nervous system.
Some studies suggest that ANKRD10 may play a role in cancer progression and metastasis. It has been implicated in promoting epithelial-mesenchymal transition (EMT) and facilitating the migration and invasion of cancer cells. However, more research is required to establish its precise contributions to cancer development.
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