Recombinant Human ARC Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARC-596H
• Product Overview: ARC MS Standard C13 and N15-labeled recombinant protein (NP_056008) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.3 kDa
• AA Sequence: MELDHRTSGGLHAYPGPRGGQVAKP NVILQIGKCRAEMLEHVRRTHRHLL AEVSKQVERELKGLHRSVGKLESNL DGYVPTSDSQRWKKSIKACLCRCQE TIANLERWVKREMHVWREVFYRLER WADRLESTGGKYPVGSESARHTVSV GVGGPESYCHEADGYDYTVSPYAIT PPPAAGELPGQEPAEAQQYQPWVPG EDGQPSPGVDTQIFEDPREFLSHLE EYLRQVGGSEEYWLSQIQNHMNGPA KKWWEFKQGSVKNWVEFKKEFLQYS EGTLSREAIQRELDLPQKQGEPLDQ FLWRKRDLYQTLYVDADEEEIIQYV VGTLQPKLKRFLRHPLPKTLEQLIQ RGMEVQDDLEQAAEPAGPHLPVEDE AETLTPAPNSESVASDRTQPETRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARC activity-regulated cytoskeleton-associated protein [ Homo sapiens (human) ]
• Official Symbol: ARC
• Synonyms: ARC; activity-regulated cytoskeleton-associated protein; Arg3.1; KIAA0278; ARC/ARG3.1; activity-regulated gene 3.1 protein homolog
• Gene ID: 23237
• mRNA Refseq: NM_015193
• Protein Refseq: NP_056008
• MIM: 612461
• UniProt ID: Q7LC44