Active Recombinant Full Length Human DUSP13B Protein, N-GST-tagged
| Cat.No. : | DUSP13B-177HFL |
| Product Overview : | N-terminal GSTtagged, recombinant, human TMDP, full length, expressed in E. coli cells. Purified using glutathione agarose. |
- Specification
- Gene Information
- Related Products
| Description : | TMDP, also known as DUSP13 (Dual Specificity Phosphatase 13), is a member of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotryosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. |
| Source : | E. coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | Full Length |
| Form : | 4.35mg/ml of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Bio-activity : | 2115U/mg, where one unit of TMDP activity is defined as the release of 1nmol of phosphate per minute from the phosphorylated substrate 6,8-difluoro-4- methylumbelliferyl phosphate (DiFMUP) at room temperature. |
| Molecular Mass : | 49 kDa |
| AA Sequence : | 1 MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID 61 GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV 121 DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK 181 KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSPEFM DSLQKQDLRR 241 PKIHGAVQAS PYQPPTLASL QRLLWVRQAA TLNHIDEVWP SLFLGDAYAA RDKSKLIQLG 301 ITHVVNAAAG KFQVDTGAKF YRGMSLEYYG IEADDNPFFD LSVYFLPVAR YIRAALSVPQ 361 GRVLVHCAMG VSRSATLVLA FLMIYENMTL VEAIQTVQAH RNICPNSGFL RQLQVLDNRL 421 GRETGRF |
| Purity : | Purity 99% by SDS-PAGE and Coomassie blue staining. |
| Applications : | Drug Discovery & Development |
| Storage : | 1 year at -70 centigrade. |
| Handling Advice : | Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into prechilled micro-centrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70 centigrade. |
| Use/Stability : | On receipt of material store at -70 centigrade. Unopened reagent is stable for a minimum of 1 year from date of shipment when stored at recommended storage temperature. Avoid repeat freeze/thaw cycles. For maximum recovery of product, centrifuge original vial prior to removing the cap. |
| Gene Name : | DUSP13B dual specificity phosphatase 13B [ Homo sapiens (human) ] |
| Official Symbol : | DUSP13B |
| Synonyms : | DUSP13B; dual specificity phosphatase 13B; MDSP; TMDP; SKRP4; DUSP13 |
| Gene ID : | 51207 |
| mRNA Refseq : | NM_016364.3 |
| Protein Refseq : | NP_057448.3 |
| MIM : | 613191 |
| UniProt ID : | Q9UII6 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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