Recombinant Human Polyglutamine Binding Protein 1, His-tagged
Cat.No. : | PQBP1-6773H |
Product Overview : | Recombinant humanPQBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PQBP1-6773H |
Description : | Polyglutaminebinding protein 1, also known as PQBP1, is a transcription repressor thatassociates with polyglutamine tract-containing transcription regulators andcausative genes for neurodegenerative disorders. PQBP-1 localizes to thenucleus and is present in neurons throughout the brain, with abundant levelsin hippocampus, cerebellar cortex and olfactory bulb. PQBP-1 contains aWWP/WW domain that binds proline-rich motifs and a C2 domain that caninfluence Ca2+-dependent phospholipid signaling |
Form : | Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT |
Molecular Weight : | 33 kDa (289aa),confirmed by MALDI-TOF |
Purity : | > 95% by SDS -PAGE |
Concentration : | 0.5 mg/ml(determined by Bradford assay) |
Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSHMPLPVA LQTRLAKRGI LKHLEPEPEE EIIAEDYDDD PVDYEATRLE GLPPSWYKVFDPSCGLPYYWNADTDLVSWL SPHDPNSVVT KSAKKLRSSN ADAEEKLDRS HDKSDRGHDK SDRSHEKLDRGHDKSDRGHD KSDRDRERGY DKVDRERERD RERDRDRGYD KADREEGKER RHHRREELAP YPKSKKAVSRKDEELDPMDP SSYSDAPRGT WSTGLPKRNE AKTGADTTAA GPLFQQRPYP SPGAVLRANA EASRTKQQD |
Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | PQBP1 polyglutamine bindingprotein 1 [Homo sapiens] |
Official symbol : | PQBP1 |
Synonyms : | polyglutaminebinding protein 1; SHS; NPW38; mental retardation, X-linked 55; Polyglutaminetract-binding protein 1; Sutherland-Haan X-linked mental retardationsyndrome; 38 kDa nuclear protein containing a WW domain; OTTHUMP00000025809;OTTHUMP00000025812; MRX55; nuclear protein containing WW domain 38 kD; MRXS3;polyglutamine-binding protein 1; MRXS8; RENS1; PQBP-1; OTTHUMP00000025808 |
Gene ID : | 10084 |
mRNA Refseq : | NM_005710 |
Protein Refseq : | NP_005701 |
MIM : | 300463 |
Uniprot ID : | O60828 |
Chromosome Location : | Xp11.23 |
Pathway : | Spliceosome, organism-specific biosystem; Spliceosome, conservedbiosystem |
Function : | DNA binding; transcription coactivator activity |
Products Types
◆ Recombinant Protein | ||
PQBP1-4310R | Recombinant Rat PQBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PQBP1-3402R | Recombinant Rhesus Macaque PQBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pqbp1-5090M | Recombinant Mouse Pqbp1 Protein, Myc/DDK-tagged | +Inquiry |
PQBP1-5512H | Recombinant Human PQBP1 Protein (Met1-Asp265), N-His tagged | +Inquiry |
PQBP1-3584R | Recombinant Rhesus monkey PQBP1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PQBP1-2903HCL | Recombinant Human PQBP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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