|Official Full Name||polyglutamine binding protein 1|
|Background||This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked mental retardation. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.|
|Synonyms||PQBP1; polyglutamine binding protein 1; mental retardation, X linked 55 , MRX55, MRXS8, RENS1, SHS, Sutherland Haan X linked mental retardation syndrome; polyglutamine-binding protein 1; 38 kDa nuclear protein containing a WW domain; Mental retardation, X linked 55; MRX55; MRXS3; MRXS8; Npw38; Nuclear protein containing WW domain 38 kD; OTTHUMP00000025808; Polyglutamine tract binding protein 1; PQBP 1; RENS1; SHS; Sutherland Haan X linked mental retardation syndrome; PQBP-1; OTTHUMP00000025809; OTTHUMP00000025812; polyglutamine tract-binding protein 1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
pqbp1 involved in several pathways and played different roles in them. We selected most pathways pqbp1 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with pqbp1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Spliceosome||HNRNPA3; RBM25; SF3B14; HNRNPA1L2; SART1; SF3B6; NCBP2; NHP2L1; SF3B3; SRSF9|
pqbp1 has several biochemical functions, for example, DNA binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by pqbp1 itself. We selected most functions pqbp1 had, and list some proteins which have the same functions with pqbp1. You can find most of the proteins on our site.
|DNA binding||RPL6; SSH2B; NUPR1; IER2; CDX1A; THAP11; KLF5; ZNF785; ZNF398; ZBTB48|
|protein C-terminus binding||ERCC1; PPP2CB; PPP1R9B; CDC20; DYNLL1; DDX1; PHB2; PFKM; CALCOCO1; SDCBP2|
|protein binding||INSIG2; PUF60; CA1; CCDC6; EIF3M; NPY2R; CBFB; ZFP64; TTN; B4GALT7|
|ribonucleoprotein complex binding||YBX2; BOP1; RNF135; ITCH; UHMK1; SRP54; PES; CKAP5; PPIH; PRMT7|
|transcription coactivator activity||ABT1; NCOA3; JMY; RNF14; CARM1; TUBB3; SP100; SMARCB1; MED7; LPIN3|
pqbp1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pqbp1 here. Most of them are supplied by our site. Hope this information will be useful for your research of pqbp1.
WBP11; GOLGA2; MAPRE1; LZTS2; SF3A2; AQR; CLTB; RCVRN; HNRNPH2; RAB8A; EEF1A1; RIF1