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Recombinant Human Retinol Binding Protein 1, Cellular, His-tagged

Cat. No.: RBP1-4746H
Product Overview: Recombinant human RBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: RBP1 (Retinol binding protein 1) belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. RBP1 can also act as a bridging molecule to recruit histone deacetylases (HDACs), proteins that function as potent regulators of gene expression. This protein is detected in nearly all the tissues with higher expression in adult ovary, pancreas, pituitary gland and adrenal gland, and fetal liver.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl
Molecular Weight: 24.7kDa (220aa), confirmed by MALDI-TOF
Purity: > 90% by SDS - PAGE
Concentration: 0.5mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSMDPPAGF VRAGNPAVAA PQSPLSPEGA HFRAAHHPRS TGSRCPGSLQ PSRPLVANWL QSLPEMPVDF TGYWKMLVNE NFEEYLRALD VNVALRKIAN LLKPDKEIVQ DGDHMIIRTL STFRNYIMDF QVGKEFEEDL TGIDDRKCMT TVSWDGDKLQ CVQKGEKEGR GWTQWIEGDE LHLEMRVEGV VCKQVFKKVQ
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Retinoic acid receptors-mediated signaling; Vitamin A and carotenoid metabolism
Gene Name: RBP1 retinol binding protein 1, cellular [ Homo sapiens ]
Official Symbol: RBP1
Synonyms: RBP1; CRBP; RBPC; CRBP1; CRBPI; CRABP-I; retinol-binding protein 1; CRBP-I; OTTHUMP00000208586; OTTHUMP00000217139; OTTHUMP00000225120; cellular retinol-binding protein I; retinol-binding protein 1, cellular; retinol-binding protein 1, cellular; Cellular retinol-binding protein I; Cellular retinol-binding protein; C
Gene ID: 5947
mRNA Refseq: NM_002899
Protein Refseq: NP_002890
MIM: 180260
UniProt ID: P09455
Chromosome Location: 3q23
Function: lipid binding; retinal binding; retinoid binding; retinol binding; transporter activity

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