"TWF1" Related Products

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Recombinant Human Twinfilin, Actin-Binding Protein, Homolog 1 (Drosophila), His-tagged

Cat. No.: TWF1-1322H
Product Overview: Recombinant human TWF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description: TWF1 is a ubiquitous actin-monomer-binding protein that is composed of two ADF-homology domains. It forms a 1:1 complex with ADP-actin-monomers, inhibits nucleotide exchange on actin monomers and prevents assembly of the monomer into filaments.
Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 40% glycerol, 0.15 M NaCl.
Molecular Weight: 31.5 kDa (277 aa) confirmed by MALDI-TOF
Purity: > 80 % by SDS-PAGE
Concentration: 0.25 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMMLYAA TRATLKKEFG GGHIKDEVFG TVKEDVSLHG YKKYLLSQSS PAPLTAAEEE LRQIKINEVQ TDVGVDTKHQ TLQGVAFPIS REAFQALEKL NNRQLNYVQL EIDIKNEIII LANTTNTELK DLPKRIPKDS ARYHFFLYKH SHEGDYLESI VFIYSMPGYT CSIRERMLYS SCKSRLLEIV ERQLQMDVIR KIEIDNGDEL TADFLYEEVH PKQHAHKQSF AKPKGPAGKR GIRRLIRGPA ETEATTD
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: superpathway of gluconate degradation
Gene Name: TWF1 twinfilin, actin-binding protein, homolog 1 (Drosophila) [ Homo sapiens ]
Official Symbol: TWF1
Synonyms: TWF1; twinfilin, actin-binding protein, homolog 1 (Drosophila); A6; PTK9; MGC23788; MGC41876; twinfilin-1; protein A6; protein tyrosine kinase 9; A6 protein tyrosine kinase; PTK9 protein tyrosine kinase 9
Gene ID: 5756
mRNA Refseq: NM_001242397
Protein Refseq: NP_001229326
MIM: 610932
UniProt ID: Q12792
Chromosome Location: 12q12
Function: ATP binding; actin monomer binding; phosphatidylinositol-4,5-bisphosphate binding; protein tyrosine kinase activity; NOT protein tyrosine kinase activity

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