Recombinant Human Tropomyosin 3, His-tagged
Cat.No. : | TPM3-4853H |
Product Overview : | Recombinant human TPM3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TPM3-4853H |
Description : | Tropomyosin alpha-3 chain, also known as TPM3, is member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing1mM DTT, 10% glycerol, 0.1M NaCl. |
Molecular Weight : | 31.6 kDa (272aa), confirmed by MALDI-TOF. |
Purity : | >90% by SDS-PAGE |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MGSHMAGITT IEAVKRKIQV LQQQADDAEE RAERLQREVE GERRAREQAE AEVASLNRRI QLVEEELDRA QERLATALQK LEEAEKAADE SERGMKVIEN RALKDEEKME LQEIQLKEAK HIAEEADRKY EEVARKLVII EGDLERTEER AELAESRCRE MDEQIRLMDQ NLKCLSAAEE KYSQKEDKYE EEIKILTDKL KEAETRAEFA ERSVAKLEKT IDDLEDKLKC TKEEHLCTQR MLDQTLLDLN EM |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Cardiac muscle contraction; Dilated cardiomyopathy; Hypertrophic cardiomyopathy (HCM); Muscle contraction; Pathways in cancer; Smooth Muscle Contraction; Striated Muscle Contraction; Thyroid cancer |
Gene Name : | TPM3 tropomyosin 3 [ Homo sapiens ] |
Official Symbol : | TPM3 |
Synonyms : | TPM3; tropomyosin 3; TM3; TRK; NEM1; TM-5; TM30; TM30nm; TPMsk3; hscp30; MGC3261; FLJ41118; MGC14582; MGC72094; OK/SW-cl.5; tropomyosin alpha-3 chain; hTM5; tropomyosin-3; tropomyosin-5; gamma-tropomyosin; tropomyosin gamma; OTTHUMP00000034016; OTTHUMP00000034018; OTTHUMP00000034019; OTTHUMP00000034020; OTTHUMP00000034021; OTTHUMP00000034171; OTTHUMP00000034172; OTTHUMP00000034173; OTTHUMP00000218067; OTTHUMP00000218071; cytoskeletal tropomyosin TM30; heat-stable cytoskeletal protein 30 kDa; Gamma-tropomyosin; Tropomyosin-3; Tropomyosin-5 |
Gene ID : | 7170 |
mRNA Refseq : | NM_001043351 |
Protein Refseq : | NP_001036816 |
MIM : | 191030 |
UniProt ID : | P06753 |
Chromosome Location : | 1q21.2 |
Function : | actin binding; molecular function |
Products Types
◆ Recombinant Protein | ||
Tpm3-471R | Recombinant Rat Tpm3 Protein, His-tagged | +Inquiry |
Tpm3-6600M | Recombinant Mouse Tpm3 Protein, Myc/DDK-tagged | +Inquiry |
TPM3-4733R | Recombinant Rhesus Macaque TPM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPM3-5900R | Recombinant Rat TPM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPM3-0145H | Recombinant Human TPM3 Protein (M2-I285), His/GST tagged | +Inquiry |
◆ Lysates | ||
TPM3-842HCL | Recombinant Human TPM3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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