Recombinant Human DGCR2, GST-tagged

• Cat.No.: DGCR2-11950H
• Product Overview: Recombinant Human DGCR2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: N-term-300a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DGCR2 DiGeorge syndrome critical region gene 2 [ Homo sapiens ]
• Official Symbol: DGCR2
• Synonyms: DGS C; DGS2; DiGeorge syndrome critical region gene 2; IDD; integral membrane protein DGCR2; LAN; SEZ 12; DiGeorge syndrome critical region protein 2; integral membrane protein deleted in DiGeorge syndrome
• Gene ID: 9993
• mRNA Refseq: NM_005137.2
• Protein Refseq: NP_005128.1
• MIM: 600594
• UniProt ID: P98153
• Chromosome Location: 22q11.21
• Function: carbohydrate binding