Recombinant Human TOP2A, GST-tagged

• Cat.No.: TOP2A-3351H
• Product Overview: Recombinant Human TOP2A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-345aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: TOP2A topoisomerase (DNA) II alpha 170kDa [ Homo sapiens ]
• Official Symbol: TOP2A
• Synonyms: TOP2A; topoisomerase (DNA) II alpha 170kDa; TOP2, topoisomerase (DNA) II alpha (170kD); DNA topoisomerase 2-alpha; DNA gyrase; DNA topoisomerase II, 170 kD; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase II, alpha isozyme; TOP2; TP2A
• Gene ID: 7153
• mRNA Refseq: NM_001067
• Protein Refseq: NP_001058
• MIM: 126430
• UniProt ID: P11388
• Chromosome Location: 17q21-q22
• Pathway: Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; G0 and Early G1, organism-specific biosystem; Mitotic G1-G1/S phases, organism-specific biosystem
• Function: ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA-dependent ATPase activity; chromatin binding; drug binding; enzyme binding; histone deacetylase binding; nucleotide binding; protein C-terminus binding; protein binding; protein h