Recombinant Human neuromedin B, His-tagged

• Cat.No.: NMB-208H
• Product Overview: NMB, 25-121aa, Human, His tag, E.coli

Specification

• Description: Neuromedin B, also known as NMB, belongs to the bombesin/neuromedin-B/ranatensin family and stimulates smooth muscle contraction in a manner similar to that of bombesin. Recombinant human NMB protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
• Molecular Mass: 13.2kDa (120aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSAPLSWDL PEPRSRASKI RVHSRGNLWA TGHFMGKKSL EPSSPSPLGT APHTSLRDQR LQLSHDLLGI LLLKKALGVS LSRPAPQIQY RRLLVQILQK
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: NMB neuromedin B [ Homo sapiens ]
• Official Symbol: NMB
• Synonyms: NMB; neuromedin B; neuromedin-B; MGC2277; MGC3936; MGC17211
• Gene ID: 4828
• mRNA Refseq: NM_021077
• Protein Refseq: NP_066563
• MIM: 162340
• UniProt ID: P08949
• Chromosome Location: 15q11-qter
• Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem
• Function: hormone activity