Recombinant Human syndecan binding protein (syntenin) 2, His-tagged

• Cat.No.: SDCBP2-385H
• Product Overview: SDCBP2, 1-292 aa, Human, His tag, E.coli

Specification

• Description: SDCBP2 contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Recombinant human SDCBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 34.0 kDa (315aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSLYPS LEDLKVDQAI QAQVRASPKM PALPVQATAI SPPPVLYPNL AELENYMGLS LSSQEVQESL LQIPEGDSTA VSGPGPGQMV APVTGYSLGV RRAEIKPGVR EIHLCKDERG KTGLRLRKVD QGLFVQLVQA NTPASLVGLR FGDQLLQIDG RDCAGWSSHK AHQVVKKASG DKIVVVVRDR PFQRTVTMHK DSMGHVGFVI KKGKIVSLVK GSSAARNGLL TNHYVCEVDG QNVIGLKDKK IMEILATAGN VVTLTIIPSV IYEHMVKKLP PVLLHHTMDH SIPDA
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SDCBP2 syndecan binding protein (syntenin) 2 [ Homo sapiens ]
• Official Symbol: SDCBP2
• Synonyms: SDCBP2; syndecan binding protein (syntenin) 2; syntenin-2; SITAC18; ST 2; ST-2; SITAC; FLJ12256
• Gene ID: 27111
• mRNA Refseq: NM_001199784
• Protein Refseq: NP_001186713
• UniProt ID: Q9H190
• Chromosome Location: 20p13
• Function: protein C-terminus binding; protein heterodimerization activity; protein homodimerization activity