Recombinant Human enolase 2, His-tagged

• Cat.No.: ENO2-108H
• Product Overview: Recombinant Human NSE comprises a 433 amino acid fragment (2-434) corresponding to processed mature NSE protein and is expressed in E. coli with an aminoterminal hexahistidine tag.

Specification

• Cat. No.: ENO2-108H
• Description: NSE is the γγ isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells . NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival.
• Source: E.coli.
• Purity: >95% by SDS-PAGE
• Form: Liquid
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: ENO2 enolase 2 (gamma, neuronal) [ Homo sapiens ]
• Synonyms: ENO2; NSE; enolase 2 (gamma, neuronal); enolase 2; neural enolase; neurone-specific enolase; neuron specific gamma enolase; 2-phospho-D-glycerate hydrolyase; EC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; 2-phospho-D-glycerate hydrolyase;Neuron-specific enolase; enolase 2 (gamma, neuronal); neuron specific gamma enolase; neurone-specific enolase.
• Gene ID: 2026
• mRNA Refseq: NM_001975
• Protein Refseq: NP_001966
• MIM: 131360
• UniProt ID: P09104
• Chromosome Location: 12p13
• Function: lyase activity; magnesium ion binding; phosphopyruvate hydratase activity