Active Recombinant Human Epidermal Growth Factor

• Cat.No.: EGF-6H
• Product Overview: Human EGF is produced by genetically engineered yeast, and purified by sequential chromatography and reverse-phase HPLC.

Specification

• Source: yeast
• Species: Human
• Form: Lyophilized powder
• Bio-activity: The mitogenic activity of human EGF is measured by the stimulation of 3H-thymidine incorporation into human foreskin fibroblast cells. In addition, EGF activity has been determined by a receptor-binding assay (RBA) using A-431 cells.
• Purity: Over 97% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis.
• Stability: Several months at +4°C. In solution, at pH 4-7, is stable for 2-3 months at -20°C.
• Storage: Store at +4°C. Reconstitution is best in water or buffer near neutral pH.

Gene Information

• Gene Name: EGF epidermal growth factor [ Homo sapiens (human) ]
• Official Symbol: EGF
• Synonyms: EGF; epidermal growth factor (beta-urogastrone); URG; HOMG4; epidermal growth factor; beta-urogastrone; Pro-epidermal growth factor; Epidermal growth factor; Urogastrone; OTTHUMP00000162922; OTTHUMP00000219721; OTTHUMP00000219722
• Gene ID: 1950
• mRNA Refseq: NM_001963
• Protein Refseq: NP_001954
• MIM: 131530
• UniProt ID: P01133
• Chromosome Location: 4q25
• Pathway: Bladder cancer; Cytokine-cytokine receptor interaction; Endocytosis; Endometrial cancer; ErbB signaling pathway; Focal adhesion; Gap junction
• Function: calcium ion binding; epidermal growth factor receptor binding; growth factor activity; protein binding; transmembrane receptor protein tyrosine kinase activator activity