Recombinant Human KIR2DL3

• Cat.No.: KIR2DL3-146H
• Product Overview: Recombinant Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 produced inE.Coliis a single, non-glycosylated polypeptide chain. The protein contains 202 amino acids and has a molecular mass of 22 kDa.

Specification

• Cat. No.: KIR2DL3-146H
• Description: An inhibitory Killer Cell Ig-like Receptor(KIR, previously called p58 KIR, cl-6, NKAT2 or KIR-K7), which recognizes class I MHC molecules(HLA-Cw1, -Cw3, -Cw7, and Cw8).
• Source: Escherichia Coli.
• Amino Acid Sequence: MEGVHRKPSL LAHPGPLVKS EETVILQCWS DVRFQHFLLH REGKFKDTLH LIGEHHDGIS KANFSIGPMM QDLAGTYRCY GSVTHSPYQL SAPSDPLDIV ITGLYEKPSL SAQPGPTVLA GESVTLSCSS RSSYDMYHLS REGEAHERRF SAGPKVNGTF QADFPLGPAT HGGTYRCFGS FRDSPYEWSN SSDPLLVSVT GN.
• Physical Appearance: Sterile filtered clorless solution.
• Formulation: The protein (1mg/ml) contains 25mM Tris-HCl (pH7.5).
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Coomassie.
• Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Gene Information

• Gene Name: KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 [ Homo sapiens ]
• Synonyms: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; p58; NKAT; GL183; NKAT2; CD158b; NKAT2A; NKAT2B; CD158B2; KIR-K7b; KIR-K7c; KIRCL23; KIR-023GB; MGC129943; KIR2DL3; NK-receptor; p58 natural killer cell receptor; natural killer associated transcript 2; p58.2 MHC class-I specific NK receptor; killer cell immunoglobulin-like receptor 2DL3; natural killer cell inhibitory receptor KIR2DL3; cl-6; nkat2; nkat2a; nkat2b; NKAT-2; NKAT2a; NKAT2b; CD158 antigen-like family member B2; CD158b2 antigen; Killer inhibitory receptor cl 2-3; MHC class I NK cell receptor; Natural killer-associated transcript 2; p58 NK receptor; p58 natural killer cell receptor clone CL-6; p58.2 MHC class-I-specific NK receptor
• Gene ID: 3804
• mRNA Refseq: NM_014511
• Protein Refseq: NP_055326
• MIM: 604938
• UniProt ID: P43628
• Pathway: Antigen processing and presentation; Graft-versus-host disease; Natural killer cell mediated cytotoxicity; Signaling in Immune system
• Function: antigen binding; receptor activity