Recombinant Human GUSB
| Cat.No. : | GUSB-27205TH |
| Product Overview : | Recombinant full length Human beta glucuronidase with N terminal proprietary tag, 95.41kDa. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. There are many pseudogenes of this locus in the human genome. |
| Protein length : | 630 amino acids |
| Molecular Weight : | 95.410kDa inclusive of tags |
| Source : | Wheat germ |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | GLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEE QWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWY EREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLE HEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTL PPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLY TTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVR LLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLY SLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGK PFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAF RTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNNV SLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGY YLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICL NSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEY GAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYV VGELIWNFADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFL LRERYWKIANETRYPHSVAKSQCLENSLFT |
| Sequence Similarities : | Belongs to the glycosyl hydrolase 2 family. |
| Gene Name : | GUSB glucuronidase, beta [ Homo sapiens ] |
| Official Symbol : | GUSB |
| Synonyms : | GUSB; glucuronidase, beta; beta-glucuronidase; |
| Gene ID : | 2990 |
| mRNA Refseq : | NM_000181 |
| Protein Refseq : | NP_000172 |
| MIM : | 611499 |
| Uniprot ID : | P08236 |
| Chromosome Location : | 7q11.21 |
| Pathway : | Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem; Chondroitin sulfate degradation, organism-specific biosystem; |
| Function : | beta-glucuronidase activity; cation binding; sugar binding; |
Products Types
| ◆ Recombinant Protein | ||
| GUSB-4015M | Recombinant Mouse GUSB Protein, His (Fc)-Avi-tagged | +Inquiry |
| GUSB-001H | Active Recombinant Human GUSB Protein | +Inquiry |
| GUSB-4500H | Recombinant Human GUSB Protein, GST-tagged | +Inquiry |
| Gusb-446M | Recombinant Mouse Gusb Protein, MYC/DDK-tagged | +Inquiry |
| GUSB-2417R | Recombinant Rat GUSB Protein, His (Fc)-Avi-tagged | +Inquiry |
| ◆ Native Protein | ||
| GUSB-12H | Active Native Helix pomatia b-Glucuronidase | +Inquiry |
| ◆ Lysates | ||
| GUSB-5673HCL | Recombinant Human GUSB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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