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Recombinant Human LTA, His-tagged

Cat.No. : LTA-31534TH
Product Overview : RecombinantHumanTNF-beta, expressed in (BTI-Tn-5B1-4) High-5 Insect Cells. This is an 18.6 kDa protein containing 172 amino acid residues. (Due to glycosylation, TNF-beta has an approximate molecular weight of 19.3 kDa.)
  • Specification
  • Gene Information
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Description : The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.
Conjugation : HIS
Form : Lyophilised:Centrifuge the vial prior to opening.Reconstitute in water to a concentration of °C for 1 week or -20°C for future use.
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg).
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids : GVGLTPSAAQ TARQHPKMHL AHSTLKPAAH LIGDPSKQNS LLWRANTDRA FLQDGFSLSN NSLLVPTSGI YFVYSQVVFS GKAYSPKATS SPLYLAHEVQ LFSSQYPFHV PLLSSQKMVY PGLQEPWLHS MYHGAAFQLT QGDQLSTHTD GIPHLVLSPS TVFFGAFAL
Sequence Similarities : Belongs to the tumor necrosis factor family.
Gene Name : LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
Official Symbol : LTA
Synonyms : LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1;
Gene ID : 4049
mRNA Refseq : NM_000595
Protein Refseq : NP_000586
MIM : 153440
Uniprot ID : P01374
Chromosome Location : 6p21.3
Pathway : Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Function : cytokine activity; receptor binding; tumor necrosis factor receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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