Recombinant Human Tyrosine 3-monooxygenase/ Tryptophan 5-monooxygenase Activation Protein, Theta Polypeptide

• Cat.No.: YWHAQ-13H
• Product Overview: Recombinant human YWHAQ was expressed inE.coliand purified by using conventional chromatography techniques, 27 kDa (245 aa).

Specification

• Cat. No.: YWHAQ-13H
• Description: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis.
• Sequences of amino acids: MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWR VISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLK MKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYE ILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA EGAEN
• Formulation: Liquid in 20 mM Tris pH 8.0
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide[ Homo sapiens ]
• Synonyms: 14-3-3 theta; 14-3-3 tau; 14-3-3 T-cell; HS1; YWHAQ; 1C5;14-3-3; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide protein tau; 14-3-3 protein tau; OTTHUMP00000015730; 14-3-3 protein theta; 14-3-3 protein T-cell; Protein HS1; tyrosine 3/tryptophan 5 -monooxygenase activation protein,theta polypeptide
• Gene ID: 10971
• mRNA Refseq: NM_006826
• Protein Refseq: NP_006817
• MIM: 609009
• UniProt ID: P27348
• Chromosome Location: 2p25.1
• Pathway: Cell cycle; Pathogenic Escherichia coli infection – EHEC; Pathogenic Escherichia coli infection - EPEC
• Function: protein N-terminus binding; protein domain specific binding