ywhaq
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  • Official Full Name
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
  • Background
  • The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma,
  • Synonyms
  • YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; 14-3-3 protein theta; 14 3 3; HS1; protein tau; 14-3-3 protein tau; 14-3-3 protein T-cell; 1C5; 14-3-3
Cat.#:YWHAQ-123HTag:MYC/DDK
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human YWHAQ protein, MYC/DDK-tagged
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Cat.#:YWHAQ-2563HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAQ, GST tagged
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Cat.#:YWHAQ-26016THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAQ, His-tagged
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Cat.#:YWHAQ-26017THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAQ
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Cat.#:YWHAQ-26019THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human YWHAQ
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Cat.#:YWHAQ-6641RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat YWHAQ Protein
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Cat.#:YWHAQ-1557CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken YWHAQ
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Cat.#:YWHAQ-230HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human YWHAQ 293 Cell Lysate
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Involved Pathway

YWHAQ involved in several pathways and played different roles in them. We selected most pathways YWHAQ participated on our site, such as Activation of BAD and translocation to mitochondria, Activation of BH3-only proteins, Alpha6-Beta4 Integrin Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with YWHAQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of BAD and translocation to mitochondria
AKT3; YWHAQ; CDK5RAP2
Activation of BH3-only proteins
E2F1; CDK5RAP2; AKT3; YWHAQ; BCL2L11; DYNLL2
Alpha6-Beta4 Integrin Signaling Pathway
DSP; NTN1A; CD151; MST1R; EIF4E; RTKN; CLCA1; CD151L; SMAD3B; YWHAQ
Apoptosis
IKBKB; CASP7; TNFSF10; TICAM1; IKBKG; BAD; CAPN2; CFLARA; BIDA; ATM
Calcium Regulation in the Cardiac Cell
RGS11; GNB3B; RGS5; CHRM4; RGS20; GJA8; GJC1; ADRA1D; ADRB2; ADRA1B
Cell Cycle
YWHAG; RBBP7; GINS3; ANKLE2; BUB3; RAD9B; MASTL; SPDL1; GINS4; POT1
Cell Cycle Checkpoints
DBF4; HTATIP; BRCC3; UIMC1; CDKN1B; RAD9A; HIST3H2BB; BARD1; CDK5RAP2; RNF168

Protein Function

YWHAQ has several biochemical functions, for example, 14-3-3 protein binding, ion channel binding, protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YWHAQ itself. We selected most functions YWHAQ had, and list some proteins which have the same functions with YWHAQ. You can find most of the proteins on our site.
Function
Related Protein
Function 14-3-3 protein binding
Related Protein HDAC7; KIF13B; PRKCZ; KCNH1; AANAT; YWHAQ; ARRB2; RPTOR; PRKCE; TSC2
Function ion channel binding
Related Protein SLC8A1; RNF207; S100A10; NOS1; PACS1; PRKCSH; SLC14A2; ID2; YWHAE; PHPT1
Function protein C-terminus binding
Related Protein CDK7; HSPB7; RABAC1; BAIAP2; PLEKHB1; HESX1; YAP1; HRAS; PQBP1; DST
Function protein N-terminus binding
Related Protein MORF4L1; SCT; ATM; TDRD7; STX1A; GLRX; STX5; ERCC3; KCNIP1; THAP7
Function protein binding
Related Protein PLOD3; F7; CD300LH; GK; GTF3C5; TTLL6; VEPH1; AP1M1; C5orf24; BMF
Function protein domain specific binding
Related Protein ARHGEF4; TJP2; HIST2H4A; ARFIP1; ARFIP2A; HAND2; MYO7A; STRN4; VRK2; PRKCZ

Interacting Protein

YWHAQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YWHAQ here. Most of them are supplied by our site. Hope this information will be useful for your research of YWHAQ.
LRRK2; EGFR; YAP1; CBL