Recombinant Human Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein
Cat.No. : | NOS1AP-636H |
Product Overview : | Recombinant Human Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein is producedinSf9 cells.MW=160kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NOS1AP-636H |
Description : | This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. |
Source : | Sf9 cells. |
Formulation : | Liquid. In 50mM triethanolamine, pH 7.5, 0.5mM EDTA, 7mM GSH, 0.2% CHAPSO, 1µm E64, 1µM leupeptin, 1µM pepstatin, 1mg/ml trypsin inhibitor and 10% glycerol. |
Specific Activity : | ≥1nmol/100μl/min (U/100μl). Amount assayed 1µl. Optimal conditions: 37°C, pH 7.0, 1mM L-arginine, 1mM NADPH, 10µM (6R)-tetrahydrobiopterin, 5µM FAD, 5µM FMN, 50nM calmodulin, 1mM CaCl2 and 7mM GSH. |
Storage : | -80°C. nNOS is relatively unstable. Keep stock vial on ice at all times when performing experiments! Enzyme loses approx. 10-15% of activity during a single freeze/thaw cycle. |
Gene Name : | NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein [ Homo sapiens ] |
Synonyms : | NOS1AP; nitric oxide synthase 1 (neuronal) adaptor protein; C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON); C-terminal PDZ ligand of neuronal nitric oxide synthase protein; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain; nitric oxide synthase 1 adaptor protein; CAPON; MGC138500; 6330408P19Rik |
Gene ID : | 9722 |
mRNA Refseq : | NM_001126060 |
Protein Refseq : | NP_001119532 |
MIM : | 605551 |
UniProt ID : | O75052 |
Chromosome Location : | 1q23.3 |
Function : | PDZ domain binding; nitric-oxide synthase binding; protein binding |
Products Types
◆ Recombinant Protein | ||
NOS1AP-1157H | Recombinant Human NOS1AP Protein, His-tagged | +Inquiry |
NOS1AP-3682R | Recombinant Rat NOS1AP Protein, His (Fc)-Avi-tagged | +Inquiry |
NOS1AP-6136M | Recombinant Mouse NOS1AP Protein, His (Fc)-Avi-tagged | +Inquiry |
NOS1AP-5990H | Recombinant Human NOS1AP Protein, GST-tagged | +Inquiry |
NOS1AP-2889R | Recombinant Rhesus Macaque NOS1AP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NOS1AP-3760HCL | Recombinant Human NOS1AP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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