Recombinant Human NOS1AP Protein, GST-tagged

• Cat.No.: NOS1AP-5990H
• Product Overview: Human NOS1AP full-length ORF ( NP_055512.1, 1 a.a. - 506 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 82.5 kDa
• AA Sequence: MPSKTKYNLVDDGHDLRIPLHNEDA FQHGICFEAKYVGSLDVPRPNSRVE IVAAMRRIRYEFKAKNIKKKKVSIM VSVDGVKVILKKKKKLLLLQKKEWT WDESKMLVMQDPIYRIFYVSHDSQD LKIFSYIARDGASNIFRCNVFKSKK KSQAMRIVRTVGQAFEVCHKLSLQH TQQNADGQEDGESERNSNSSGDPGR QLTGAERASTATAEETDIDAVEVPL PGNDVLEFSRGVTDLDAVGKEGGSH TGSKVSHPQEPMLTASPRMLLPSSS SKPPGLGTETPLSTHHQMQLLQQLL QQQQQQTQVAVAQVHLLKDQLAAEA AARLEAQARVHQLLLQNKDMLQHIS LLVKQVQELELKLSGQNAMGSQDSL LEITFRSGALPVLCDPTTPKPEDLH SPPLGAGLADFAHPAGSPLGRRDCL VKLECFRFLPPEDTPPPAQGEALLG GLELIKFRESGIASEYESNTDESEE RDSWSQEELPRLLNVLQRQELGDGL DDEIAV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein [ Homo sapiens ]
• Official Symbol: NOS1AP
• Synonyms: NOS1AP; nitric oxide synthase 1 (neuronal) adaptor protein; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; C terminal PDZ domain ligand of neuronal nitric oxide synthase; CAPON; KIAA0464; nitric oxide synthase 1 adaptor protein; C-terminal PDZ ligand of neuronal nitric oxide synthase protein; C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON); ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain; 6330408P19Rik; MGC138500
• Gene ID: 9722
• mRNA Refseq: NM_001126060
• Protein Refseq: NP_001119532
• MIM: 605551
• UniProt ID: O75052