| Description : |
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
89.5 kDa |
| AA Sequence : |
MALSSEPAEMPRQFPKLNISEVDEQ VRLLAEKVFAKVLREEDSKDALSLF TVPEDCPIGQKEAKERELQKELAEQ KSVETAKRKKSFKMIRSQSLSLQMP PQQDWKGPPAASPAMSPTTPVVTGA TSLPTPAPYAMPEFQRVTISGDYCA GITLEDYEQAAKSLAKALMIREKYA RLAYHRFPRITSQYLGHPRADTAPP EEGLPDFHPPPLPQEDPYCLDDAPP NLDYLVHMQGGILFVYDNKKMLEHQ EPHSLPYPDLETYTVDMSHILALIT DGPTKTYCHRRLNFLESKFSLHEML NEMSEFKELKSNPHRDFYNVRKVDT HIHAAACMNQKHLLRFIKHTYQTEP DRTVAEKRGRKITLRQVFDGLHMDP YDLTVDSLDVHAGRQTFHRFDKFNS KYNPVGASELRDLYLKTENYLGGEY FARMVKEVARELEESKYQYSEPRLS IYGRSPEEWPNLAYWFIQHKVYSPN MRWIIQVPRIYDIFRSKKLLPNFGK MLENIFLPLFKATINPQDHRELHLF LKYVTGFDSVDDESKHSDHMFSDKS PNPDVWTSEQNPPYSYYLYYMYANI MVLNNLRRERGLSTFLFRPHCGEAG SITHLVSAFLTADNISHGLLLKKSP VLQYLYYLAQIPIAMSPLSNNSLFL EYSKNPLREFLHKGLHVSLSTDDPM QFHYTKEALMEEYAIAAQVWKLSTC DLCEIARNSVLQSGLSHQEKQKFLG QNYYKEGPEGNDIRKTNVAQIRMAF RYETLCNELSFLSDAMKSEEITALT NTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
